Underlying immunopathology as a cause of adverse responses to two intravenous anaesthetic agents.
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چکیده
منابع مشابه
Underlying immunopathology as a cause of adverse responses to two intravenous anaesthetic agents.
A patient who had shown some evidence of immunological sensitivity underwent several operations under general anaesthesia for otitis media without ill effect. On his second exposure to Althesin, however, he suffered a severe reaction. Facial angioneurotic oedema was accompanied by peripheral vasodilatation and sweating, and C3 conversion was observed in his plasma. Subsequent anaesthetics produ...
متن کاملAdverse reactions to anaesthetic agents.
Sir,—Even though some small changes in heart rate were shown to be statistically significant, no clinical significance was attached to such changes. The study was primarily done to assess the overall need of anticholinergic premedication in patients undergoing minor surgery and as such drugs were not administered on a weight basis. However, Dr Gilmour's comment has aroused our interest in this ...
متن کاملReport of a symposium: adverse responses to intravenous agents.
An International Symposium on "Adverse Responses to Intravenous Agents" held in Sheffield, July 6-7, 1978 attracted 137 registered participants, not only from a variety of countries, but also established representatives of a number of scientific disciplines. The Symposium, organized jointly by the University of Sheffield Departments of Immunology and Anaesthetics, also coincided with the 150th ...
متن کاملVascular Responses to Anaesthetic Agents* Stewart
ALTHOUGH EFFECTS Of anaesthetic agents on cardiac haemodynamics have been defined 1,'' until recently few data have been available concerning their actions on the peripheral circulation. In this regard, probably the best studied agent is halothane. Among the pertinent observations are decreased hepatic artery resistance in dogs, 3 decreased resistance in the canine hind limb, 4 decreased total ...
متن کاملIdentification and quantitation of hypersensitivity reactions to intravenous anaesthetic agents.
It is not possible to distinguish between direct pharmacological effects and immune-mediated hypersensitivity reactions by clinical observation alone and errors may occur in the absence of laboratory tests. A convenient and simple test is the measurement of plasma complement C3 consumption and conversion in sequential blood samples taken at intervals over the 24 h following an adverse response.
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ژورنال
عنوان ژورنال: BMJ
سال: 1978
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.1.6121.1180